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Hyperhidrosis is a medical condition characterized by excessive sweating beyond what is required for normal temperature regulation. While sweating is a natural physiological response that helps cool the body, individuals with hyperhidrosis experience overactive sweat gland stimulation that may occur even in cool environments or without physical exertion.

Primary hyperhidrosis most commonly affects the:

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• underarms (axillary hyperhidrosis)

• hands (palmar hyperhidrosis)

• feet (plantar hyperhidrosis)

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For many individuals, excessive sweating can significantly impact daily comfort, confidence, clothing choices, professional interactions, social situations, and overall quality of life.

At Legacy Aesthetic Studio in Ottawa, hyperhidrosis treatments are designed to help reduce excessive perspiration using clinically established neuromodulator therapy tailored to the individual treatment area and severity.

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Only covered by insurance with an MD diagnosis (Family doctor or specialist). ​

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How Hyperhidrosis Treatment Works

Neuromodulators such as Botox® work by temporarily blocking the chemical signals released by nerves that activate sweat glands.

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Normally, the sympathetic nervous system stimulates eccrine sweat glands through the neurotransmitter acetylcholine. In individuals with hyperhidrosis, these signals become excessive or overactive, causing disproportionate sweating.

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When Botox® is carefully injected into the treatment area:

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• nerve signalling to sweat glands is reduced

• sweat production decreases

• moisture levels become more manageable

• comfort and confidence improve

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The treatment does not permanently damage sweat glands. Over time, nerve signaling gradually returns and maintenance treatments may be recommended.

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Common Areas Treated

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Underarm Hyperhidrosis (Axillary Hyperhidrosis)

Underarm sweating is one of the most common forms of hyperhidrosis and may lead to:

• visible sweat stains

• clothing discoloration

• odor concerns

• social anxiety

• daily discomfort

Botox® for axillary hyperhidrosis is Health Canada and FDA-approved and has been extensively studied in medical literature.

Many patients experience a dramatic reduction in underarm sweating after treatment.

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Hand Sweating (Palmar Hyperhidrosis)

Excessive palm sweating may interfere with:

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• handshakes

• typing

• gripping objects

• writing

• professional interactions

• athletic activities

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Palmar hyperhidrosis treatments may help improve daily functionality and confidence.​

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Foot Sweating (Plantar Hyperhidrosis)

Plantar hyperhidrosis may contribute to:

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• moisture buildup in shoes

• discomfort

• skin irritation

• odor

• sock saturation

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Targeted neuromodulator therapy may help support comfort and moisture reduction.

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Clinical Evidence & Patient Satisfaction

Botox® has been extensively researched for the treatment of hyperhidrosis and remains one of the most widely performed non-surgical medical treatments for excessive sweating worldwide.

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Clinical studies have demonstrated:

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• significant sweat reduction

• improved quality of life

• high patient satisfaction

• long-lasting symptom control​

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A pivotal multicenter clinical trial published in Dermatologic Surgery demonstrated substantial reductions in sweat production and significant improvements in patient-reported quality-of-life outcomes following Botox® treatment for axillary hyperhidrosis.

Additional research has shown that many patients experience meaningful symptom relief for approximately 4–6 months following treatment.

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Who is a Candidate?

Hyperhidrosis treatment may be appropriate for individuals experiencing:

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• excessive underarm sweating

• sweating unrelated to exercise or temperature

• visible perspiration through clothing

• palm sweating affecting work or social interactions

• excessive foot moisture​

Treatment plans are personalized based on anatomy, sweating patterns, lifestyle, and treatment goals.

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Clinical References & Medical Resources

1. Treatment of Hyperhidrosis With Botox (onabotulinumtoxinA): Development, Insights, and Impact.
Medicine. 2023. Lowe N, Naumann M, Eadie N.RCT

2. Botulinum Toxin: Pharmacology and Injectable Administration for the Treatment of Primary Hyperhidrosis.
Journal of the American Academy of Dermatology. 2020. Nawrocki S, Cha J.

3. Botulinum Toxin A for Axillary Hyperhidrosis (Excessive Sweating). The New England Journal of Medicine.
2001. Heckmann M, Ceballos-Baumann AO, Plewig G, Hyperhidrosis Study Group.

4. The Etiology, Diagnosis, and Management of Hyperhidrosis: A Comprehensive Review: Therapeutic
Options. Journal of the American Academy of Dermatology. 2019. Nawrocki S, Cha J.

5. Hyperhidrosis: Management Options. American Family Physician. 2018. McConaghy JR, Fosselman D.

6.FDA Orange Book. FDA Orange Book. 2026.

7. Efficacy and Safety of Botulinum Toxin Type a in Primary Axillary Hyperhidrosis: A Meta-Analysis and
Systematic Review. Aesthetic Plastic Surgery. 2025. Sun J, Chen S, Yang T, et al.

8. Beyond the Axilla: The Evolving Role of Botulinum Toxin in the Treatment of Facial, Scalp, and Focal
Hyperhidrosis. Clinics in Dermatology. 2026. Farah J, Hanna E, Aad S, Karam C, Ghanem A.

9. Treatment of Hyperhidrosis With Botulinum Toxin. Aesthetic Surgery Journal. 2012. Doft MA, Hardy KL,
Ascherman JA.

15. The Place of Botulinum Toxin Type a in the Treatment of Focal Hyperhidrosis. The British Journal of
Dermatology. 2004. Lowe N, Campanati A, Bodokh I, et al.

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